Molecular machines stop cancer’s clock
The Synthetic Biology and Drug Discovery group focuses on re-engineering bacteria and yeast for use as microscopic drug factories, and in the manipulation of mammalian gene expression.
Large, high quality libraries of new drugs are absolutely essential resources to find new medicines. However, their use is restricted to a few pharmaceutical giants. We are engineering cells to make a wide variety of drug-like molecules, providing a unique drug discovery resource accessible to almost any scientific laboratory. As each cell can make a different molecule of interest, billions of different potential drugs could be produced in a single tube. This technology provides an opportunity to put the future of drug discovery in the hands of the wider scientific community and provides new tools for Australian industries. Furthermore, these synthetic biology studies will provide insights into the fundamental biological processes that are essential for all living cells.