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The Iron Metabolism Laboratory investigates the molecular mechanisms in normal iron metabolism and in the development of iron overload disorder hereditary haemochromatosis. We use transgenic murine models of iron overload and tumor cell lines to investigate cellular iron transport using radiolabelled tracers and expression of iron transporters and regulators of iron homeostasis. We have expertise in the area of molecular and cellular biology of iron including cell isolation and culture, iron transport, gene and protein expression, gene knockdown and immunohistochemistry. Our experience in these areas should be useful for participants in the ARC Metals in Medicine Network for the testing or screening of metals or metal complexes in biological systems.


Walking in Dublin for cancer research in Perth

In so many ways COVID-19 has joined necessity as the mother of invention. For Irish grandmother, Anne Winslow, the pandemic cancelled a trip to Perth and a chance to be a part of one of WA’s biggest charity walks to raise funds for cancer research – a disease she knew…

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Boost for liver cancer patients with new $10.8 million world-class research centre

Patients with primary liver cancer will benefit from a new $10.8 million research centre established with a $5 million Cancer Research Trust grant and $5.8 million from Minderoo Foundation, Curtin University, The University of Western Australia, Harry Perkins Institute of Medical Research, the State Government and charitable organisations. Primary liver…

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Ground-breaking COVID-19 Vaccine Trial Underway in Perth: First Participants Dosed After Thousands Register

An unprecedented number of people signed up to help in the fight against COVID-19 with more than 4000 registering for a ground-breaking vaccine trial at the Perkins trials facility, Linear Clinical Research. The vaccine candidate S-Timer was one of the first protein-based COVID-19 vaccine candidates in the world to initiate…

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