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RESEARCH OVERVIEW

The Iron Metabolism Laboratory investigates the molecular mechanisms in normal iron metabolism and in the development of iron overload disorder hereditary haemochromatosis. We use transgenic murine models of iron overload and tumor cell lines to investigate cellular iron transport using radiolabelled tracers and expression of iron transporters and regulators of iron homeostasis. We have expertise in the area of molecular and cellular biology of iron including cell isolation and culture, iron transport, gene and protein expression, gene knockdown and immunohistochemistry. Our experience in these areas should be useful for participants in the ARC Metals in Medicine Network for the testing or screening of metals or metal complexes in biological systems.

LATEST NEWS

COVID-19 statement

As concerns about the spread of Coronavirus (COVID-19) in Australia increase, we wanted to assure you that our commitment to undertaking research that constantly moves our community closer to new treatments and cures for major diseases is unchanged. Our researchers will continue to work towards better outcomes for people facing…

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Treating disease from a new angle

Many different diseases have been linked to stiffness in our cells, but researchers have needed more advanced tools to examine stiffness at a microscopic level. Now, biomedical engineers at the Harry Perkins Institute of Medical Research could change that with the development of a new technology which offers a three-dimensional…

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Game-changing study shows ‘hands off’ approach’ best to treat a collapsed lung

It’s the basic rule of medicine all doctors follow – ‘first do no harm’. New research from a collaboration between Australian and New Zealand researchers backs that premise, showing that a novel ‘hands off’ approach to treating a common lung condition not only lessens pain, but significantly reduces injury, infection…

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