Synthetic biology and drug discovery

Selected publications

  1. Coquille S, Filipovska A, Chia T, Rajappa L, Lingford JP, Razif MF, Thore S, Rackham O. 2014. An artificial PPR scaffold for programmable RNA recognition. Nature Communications. 5:5729. [NCBI PubMed Entry]
  2. Thyer R, Filipovska A, Rackham O. 2013. Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation.Journal of the American Chemical Society 135(1):2-5. [NCBI PubMed Entry]
  3. Filipovska A, Rackham O. 2012. Modular recognition of nucleic acids by PUF, TALE and PPR proteins. Molecular Biosystems 8(3):699-708. [NCBI PubMed Entry]
  4. Filipovska A, Razif MF, Nygård KK, Rackham O. 2011. A universal code for RNA recognition by PUF proteins. Nature Chemical Biology7(7):425-7. [NCBI PubMed Entry]
  5. Filipovska A, Rackham O. 2011. Designer RNA-binding proteins: New tools for manipulating the transcriptome. RNA Biology 8(6):978–83. [NCBI PubMed Entry]
  6. Filipovska A, Rackham O. 2008. Building a parallel metabolism within the cell. ACS Chemical Biology 3(1):51-63. [NCBI PubMed Entry]
  7. Rackham O, Wang K, Chin JW. 2006. Functional epitopes at the ribosome subunit interface. Nature Chemical Biology 2(5):254-8. [NCBI PubMed Entry]
  8. Rackham O, Chin JW. 2005. Cellular logic with orthogonal ribosomes. Journal of the American Chemical Society 127(50):17584-5. [NCBI PubMed Entry]
  9. Rackham O, Chin JW. 2005. A network of orthogonal ribosome·mRNA pairs. Nature Chemical Biology 1(3):159-66. [NCBI PubMed Entry]
  10. Rackham O, Brown CM. 2004. Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs. EMBO Journal 23(16):3346-55. [NCBI PubMed Entry]
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