Targeted drug delivery, imaging and therapy


Selected publications

  1. Johansson A, Hamzah J, Ganss R. 2012. Intratumoral TNFα improves immunotherapy. Oncoimmunology 1(8):1395-7. [NCBI PubMed Entry]
  2. Johansson A*, Hamzah J*, Payne CJ, Ganss R. 2012. Tumor-targeted TNFα Stabilizes Tumor Vessels and Enhances Active Immunotherapy. PNAS 109 (20):7841-6. * co-first author. [NCBI PubMed Entry]
  3. Erster O, Thomas JM, Hamzah J, Jabaiah AM, Getz JA, Schoep TD, Hall SS, Ruoslahti E, Daugherty PS. 2012. Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases. Journal of Controlled Release 161(3):804-12. [NCBI PubMed Entry]
  4. Roth L, Agemy L, Kotamraju VR, Braun G, Teesalu T, Sugahara KN, Hamzah J, Ruoslahti E. 2012. Transtumoral targeting enabled by a novel neuropilin-binding peptide. Oncogene 31(33):3754-63. [NCBI PubMed Entry]
  5. Hamzah J, Kotamraju VR, Seo JW, Agemy L, Fogal V, Mahakian LM, Peters D, Roth L, Gagnon MK, Ferrara KW, Ruoslahti E. 2011. Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice. PNAS 108(17):7154-9. [NCBI PubMed Entry]
  6. Hamzah J, Altin JG, Herringson T, Parish CR, Hämmerling GJ, O'Donoghue H, Ganss R. 2009. Targeted delivery of TRL9 ligands activates spontaneous anti-tumor immunity in an autochthonous tumor model. Journal of Immunology 183(2):1091-8. [NCBI PubMed Entry]
  7. Manzur M, Hamzah J, Ganss R. 2009. Modulation of G protein Signaling Normalizes Tumor Vessels. Cancer Research 69(2):396-9. [NCBI PubMed Entry]
  8. Manzur M, Hamzah J, Ganss R. 2008. Modulation of the "blood-tumor" barrier improves immunotherapy. Cell Cycle 7(16):2452-5. [NCBI PubMed Entry]
  9. Hamzah J, Jugold M, Kiessling F, Rigby P, Manzur M, Marti HH, Rabie T, Kaden S, Gröne HJ, Hämmerling GJ, Arnold B, Ganss R. 2008. Vascular normalization in Rgs5-deficient tumours promotes immune destruction. Nature 453(7193):410-4. [NCBI PubMed Entry] [Nature Website]
  10. Hamzah J, Nelson D, Moldenhauer G, Arnold B, Hämmerling GJ, Ganss R. 2008. Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice. The Journal of Clinical Investigation 118(5):1691-9. [NCBI PubMed Entry]
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