Student project opportunities


Studying with us

If you are interested in a student project or volunteering for laboratory experience, please contact the Laboratory Head you would like to work with. 

With new facilities, the latest technology and many opportunities for formal and informal collaboration it is an exciting time to study at the Perkins. We have entered a new era with our two new research centres at Nedlands and Murdoch. The building at Nedlands, the main headquarters of the Perkins, is located at the QEII Medical Centre.

Scholarships and awards
Various scholarships and awards are available. For further information see scholarships

Project opportunities
See below the projects opportunities offered in 2017/2018.


Cancer and cell biology

Cancer Epigenetics Laboratory

  • Development of a novel strategy using engineered peptides to selectively sensitise metastatic breast cancers to chemotherapy agents 
  • Engineering the cancer epigenome and targeting metastatic behaviour using CRISPR/Cas9 
  • Discovery and characterisation of new oncogenic drivers in breast cancer

Cell Signalling Laboratory

  • Signalling networks in the regulation of red blood cell
  • Control of bone cancer cell migration and invasion by the scaffold protein AFAP1L1

Laboratory for Cancer Medicine

  • Understanding the role of mirR-7 replacement therapy in liver cancer and to identify its potential in overcoming therapeutic resistance
  • Assessing the role of thyroid receptor beta in breast cancer
  • Reprograming metastatic tumours: Exploring the roles of ZNF family transcription factors
  • Investigating the therapeutic potential of ciclopirox olamine for treatment of prostate cancer (or metastatic melanoma)

Systems Biology and Genomics Laboratory

  • Enhancer elements in human disease
  • Single cell transcriptomics
  • Multicellularity and disease
  • ZENBU Genome browser – data visualisation, statistics, peer-to-peer, cloud, integration
  • General call – Systems Biology, genomics, transcriptomics and bioinformatics

Targeted Drug Delivery, Imaging and Therapy Laboratory

  • Designing targeted nanoparticle delivery for diagnostic imaging of cancers
  • Developing recombinant proteins for tumour-specific delivery

Vascular Biology and Stromal Targeting Laboratory

  • Analysing the “Blood-Tumour”-Barrier

 

Clinical science

Centre for Clinical Research in Emergency Medicine

  • Relationship between fluid resuscitation and the endothelium in sepsis-associated coagulopathy
  • Anaphylaxis and Snakebite: Mechanisms of activation of immune cells by antivenoms
  • MicroRNAs as biomarkers for the diagnosis of critical illness
  • Unravelling the association between delirium and attendance by older people from aged care to the emergency department
  • Developing a 3D blood vessel model for the invitro assessment of critical illness
  • Assessing the suitability of the ROTEM delta to diagnose venom-induced coagulopathy

Translational Renal Research Laboratory

  • Mesothelial cell biology and host-pathogen interactions in peritoneal dialysis patients
  • Culture-independent microbiology and improving outcomes for patients with sepsisThe systems biology of sepsis
  • The impact of kidney disease on immune function

Centre for Diabetes Research

  • Genetic analyses of type 1 diabetes
  • Finding a cure for diabetic retinopathy
  • Identifying who is most likely to die from heart disease
  • Identifying genetic signatures of high risk cancer

Vascular Engineering Laboratory

  • Computational modelling of retinal haemodynamics
  • Haemodynamics in the coronary arteries
  • Cardiovascular applications of 3D bioprinting
  • Full body simulation of blood flow
  • What causes iliac artery aneurysms?

 

Molecular medicine

Epigenetics and Genomics Laboratory

  • Identifying the regulatory factors associated with neuronal maturation in vivo
  • Computational reconstruction of chromatin structure from DNA methylation profiles

Molecular Endocrinology and Pharmacology Laboratory

  • Investigation of G Protein-Coupled Receptor Molecular Pharmacology

Mitochondrial Medicine and Biology Laboratory

  • Identifying the genetic causes of mitochondrial diseases
  • Characterising the pathology of mitochondrial diseases
  • The role of mitochondrial function in diabetes and obesity

Neurogenetic Diseases Laboratory

  • Disease gene discovery for (neuro)genetic diseases
  • Pathobiology of genetic diseases
  • Devising and evaluating therapies for neurogenetic diseases
  • Identifying the genetics and pathobiology of neuromuscular diseases presenting before or at birth
  • Systematic assessment of autophagy inducers for ability to remove pathogenic cellular ALS protein aggregates

Synthetic Biology and Drug Discovery Laboratory

  • Using synthetic biology to create new therapeutics
  • Genetic selection of unnatural antibiotics
  • Targeting non-coding RNAs with artificial proteins
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