Dr Barry Doyle


Dr Barry DoyleLaboratory Head, Vascular Engineering
Email: Barry.Doyle@uwa.edu.au

Profile

Dr Barry Doyle is a National Health and Medical Research Council (NHMRC) RD Wright Biomedical Fellow and Head of Vascular Engineering at the Perkins and The University of Western Australia.

Barry has a Bachelor of Engineering (2005) and PhD (2009) both in Biomedical Engineering from The University of Limerick, Ireland. In 2010, he won a Marie Curie Fellowship and moved to the British Heart Foundation Centre for Cardiovascular Science at The University of Edinburgh, where he remains an Honorary Fellow. In 2012, he won the UWA Post-doctoral Research Fellowship which relocated him to UWA. In 2014, he won a NHMRC Career Development Fellowship – one of only two Fellowships awarded to an engineer that year – and in 2015, secured a tenure-track position as Senior Lecturer in the Faculty of Engineering, Computing and Mathematics (ECM) at UWA. Barry is a founding member of the BioZone – a WA initiative aimed at convergent science to accelerate discovery and translation in biomedical and bioengineering research. In 2016, he took over the leadership (with Brendan Kennedy and Tim Sercombe) of the ECM Bioengineering Network and most recently was offered a joint-appointment between ECM and the Perkins, and relocated to the QEII campus to establish the Biomedical Engineering@Perkins initiative.

Barry publishes widely in the top clinical, biomedical engineering and interdisciplinary journals. He is an editor of the annual Computational Biomechanics for Medicine book series (Springer) and has recently co-written a new teaching textbook on Cardiovascular Biomechanics(Springer). He is on the editorial board of the Journal of Endovascular Therapy and a guest editor for two other journals. He leads numerous national and international collaborations with top universities such as Imperial College London and University of Edinburgh, and has won over 25 different awards for his research.

Research overview

In 2014, Barry established the Vascular Engineering Laboratory (VascLab) at UWA. VascLab focusses primarily on applying cutting-edge engineering techniques to better understand vascular physiology and treat disease.

A longstanding interest is aortic aneurysms and much of his work has aimed at developing new predictive tools to determine aneurysm rupture risk through computational biomechanics. Computational and experimental methods are applied to many different forms of cardiovascular health and disease, with projects ranging from investigating the haemodynamics within the vasculature of healthy mouse placenta, to the development of thrombus in huge aortic aneurysms.

Selected publications

  1. Doyle, B.J., A. Callanan, P.E. Burke, P.A. Grace, M.T. Walsh, D.A. Vorp, and T.M. McGloughlin, Vessel Asymmetry as an Additional Diagnostic Tool for the Assessment of Abdominal Aortic Aneurysms, Journal of Vascular Surgery, 2009;49(2):443-454. [NCBI PubMed Entry]
  2. McGloughlin, T.M. and B.J. Doyle, New Approaches to Abdominal Aortic Aneurysm Assessment – Engineering Insights with Clinical Gain, Arteriosclerosis, Thrombosis and Vascular Biology, 2010;30:1687-1694. Cover image. [NCBI PubMed Entry]
  3. Doyle, B.J., A.J. Cloonan, M.T. Walsh, D.A. Vorp and T.M. McGloughlin, Identification of Rupture Locations in Patient-Specific Abdominal Aortic Aneurysms Using Experimental and Computational Techniques, Journal of Biomechanics, 2010;43(7):1408-1416. [NCBI PubMed Entry]
  4. Doyle, B.J., A. Callanan, P.A. Grace and E.G. Kavanagh, On the Influence of Patient-Specific Material Properties in Computational Simulations: A Case Study of a Large Ruptured Abdominal Aortic Aneurysm, International Journal of Numerical Methods in Biomedical Engineering, 2013;29:150-164. [NCBI PubMed Entry]
  5. Doyle, B.J., T.M. McGloughlin, K. Miller, J.T. Powell and P.E. Norman, Regions of High Wall Stress Can Predict the Future Location of Rupture of Abdominal Aortic Aneurysm, Cardiovascular and Interventional Radiology, 2014;37:815-18. [NCBI PubMed Entry]
  6. OLeary, S.A., E.G. Kavanagh, P.A. Grace, T.M. McGloughlin and B.J. Doyle, The Biaxial Mechanical Behaviour of Abdominal Aortic Aneurysm Intraluminal Thrombus: Classification of Morphology and the Determination of Layer and Region Specific Properties, Journal of Biomechanics, 2014;47:1430-37. [NCBI PubMed Entry]
  7. OLeary, S.A., D.A. Healey, E.G. Kavanagh, M.T. Walsh, T.M. McGloughlin and B.J. Doyle, The Biaxial Biomechanical Behaviour of Abdominal Aortic Aneurysm Tissue, Annals of BiomedicalEngineering, 2014;43:2440-50. [NCBI PubMed Entry]
  8. OLeary, S.A., J.J. Mulvihill, H.E. Barrett, E.G. Kavanagh, M.T. Walsh, T.M. McGloughlin and B.J. Doyle, Determining the Influence of Calcification on the Failure Properties of Abdominal Aortic Aneurysm Tissue, Journal of the Mechanical Behaviour of Biomedical Materials, 2015;42:154-167. [NCBI PubMed Entry]
  9. Joldes, G.R., K. Miller, A. Wittek and B.J. Doyle, A Simple, Effective and Clinically Applicable Method to Compute Abdominal Aortic Aneurysm Wall Stress, Journal of the Mechanical Behaviour of Biomedical Materials, 2015, in press. DOI:10.1016/j.jmbbm.2015.07.029 [NCBI PubMed Entry]
  10. Doyle, B.J. and P.E. Norman, Computational Biomechanics in Thoracic Aortic Detection: Todays Approaches and Tomorrows Opportunities, Annals of Biomedical Engineering, 2016;44(1):71-83.Cover image. [NBCI PubMed entry]
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