Category

Molecular Medicine

CancerChronic Kidney DiseaseDisease AreaLabMolecular Endocrinology and PharmacologyMolecular MedicineNews & EventsResearchResearch Area

New way to examine how medicines act on cells

By | Cancer, Chronic Kidney Disease, Disease Area, Lab, Molecular Endocrinology and Pharmacology, Molecular Medicine, News & Events, Research, Research Area

Using a genome editing technique called CRISPR/Cas9, the researchers attached a super-bright glowing molecule, derived from deep sea shrimp, to specific molecules important for signalling in cancer cells, ‘receptors’. Receptors…

Disease AreaHeartLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch AreaSynthetic Biology and Drug Discovery

Perkins researchers find essential gene for healthy hearts

By | Disease Area, Heart, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research Area, Synthetic Biology and Drug Discovery

Professor Aleksandra Filipovska and her team from the Perkins Mitochondrial Medicine and Biology Laboratory in collaboration with Professor Oliver Rackham and Professor Nils Göran Larsson and his team from the Max Planck Institute for Biology…

Disease AreaGenesLabMolecular MedicineMusclesNeurogenetic DiseasesNews & EventsResearchResearch Area

Perkins researchers decipher world-first muscle disorder cases

By | Disease Area, Genes, Lab, Molecular Medicine, Muscles, Neurogenetic Diseases, News & Events, Research, Research Area

During their investigation the multi-national team of researchers studied a muscle protein that is strongly influenced by calcium. The protein, known as tropomyosin-3 (TPM3), is vital for skeletal muscle development…

Disease AreaLabMitochondrial diseaseMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area

Cause of mitochondrial dysfunction discovered by Perkins researchers

By | Disease Area, Lab, Mitochondrial disease, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research Area

The disease, known as Leigh Syndrome, has previously been linked to a genetic mutation, but Perkins researchers were able to determine how the mutation led to mitochondrial dysfunction. Mitochondria are…

Disease AreaLabLiver DiseaseMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area

Mitochondria link to Fatty Liver Disease

By | Disease Area, Lab, Liver Disease, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research Area

Perkins researcher, Dr Tara Richman from the Mitochondrial Medicine and Biology Laboratory, was lead author on the paper Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction, recently accepted…

Disease AreaGenesLabMolecular MedicineMusclesNeurogenetic DiseasesNews & EventsResearchResearch Area

Sharpening the focus on muscle diseases

By | Disease Area, Genes, Lab, Molecular Medicine, Muscles, Neurogenetic Diseases, News & Events, Research, Research Area

Dr Gina Ravenscroft, who is lead author of the review published by the prestigious journal Brain, works in the Neurogenetic Diseases Laboratory at the Harry Perkins Institute of Medical Research; one of the world's…